Xiaohui Zhou

Xiaohui Zhou smiling

Email: xiaohui.zhou@uconn.edu
Phone: (860) 486-8743

Education

  • Ph.D. 2008 Microbiology, Washington State University, Pullman, WA
  • M.S.2004 Molecular Biology, Yangzhou University, Jiangsu, China

Professional Experience

  • 2013-Present Assistant Professor. Department of Pathobiology, University of Connecticut, Storrs, CT.
  • 2010-2013 Postdoctoral fellow. Howard Hughes Medical Institute/Harvard Medical School, Boston, MA.
  • 2008-2010 Postdoctoral fellow. Washington State University, Pullman, WA.

Courses Taught

  • Microbial Pathogenesis

Research Interests

Understand how environmental signals regulate bacterial virulence gene expression.

We are interested in elucidating how Vibrio parahaemolyticus, the most common seafood-borne pathogen causing diarrhea worldwide, activates its main virulence genes (encoding type 3 secretion systems) in response to the gastrointestinal environment.

Understand how bacterial effectors interfere with host signaling pathways.

We are interested in the mechanisms by which effectors of V. parahaemolyticus contribute to intestinal colonization, disruption of epithelial tight junctions and homeostasis of intestinal crypt cells.

Understand the genetic bases of host responses to bacterial infection

We use transcriptomic and proteomic approaches to dissect the pathways that are altered by V. parahaemolyticus infection.

Publications

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