Research
The Department of Pathobiology has numerous active research programs involving faculty members, graduate students, and staff members. Our research programs drive innovation related to several pathologic aspects of infectious and chronic diseases of both human and animals, including vaccine and virology development, environmental contaminants, and genetic sequencing of disease.
Developing a Zika Vaccine
COVID-19 Research
Research Categories
Bacterial Pathogenesis
Several labs in our department dissect the molecular underpinnings of the virulence and pathogenesis of infectious bacteria. We use this information to rationally design subunit and live attenuated vaccines, as well as to develop novel antibiotics and therapeutics.
Respiratory Infections
Our work on infectious diseases of the respiratory tract is leading to new vaccines and other solutions for diseases such as pneumonia and bronchitis. This work extends into human and veterinary respiratory pathogens, which impacts both community and agricultural health.
Virology and Vaccines
Faculty and graduate students in the Department of Pathobiology study virology and develop vaccines to address these threats to human and animal health. Our recent vaccine work includes work on the Zika Virus and COVID-19.
Molecular Epidemiology
We use an interdisciplinary combination of high-throughput genome sequencing, computational biology, phylogenetic analysis, and traditional molecular biology and virology. We hope that, through our research, we can better understand the genetic diversity and evolutionary dynamics of rapidly mutating viruses in animals.
Vector-Borne Diseases
Mosquitos, ticks, and fleas all transmit diseases to humans and animals - creating serious health conditions. Our team is involved in research and surveillance of vector-borne diseases like Lyme disease, Zika, and mor. We are studying transmission, developing preventative measures, and assessing health threats.
Centers and Institutes
The Department of Pathobiology is home to internationally recognized centers of research. We also understand the importance of multi-disciplinary collaboration across the University and beyond.
Center of Excellence for Vaccine Research
The Center of Excellence for Vaccine Research uses research expertise and a collaborative approach to study and develop vaccines for human and animal diseases. Members of the center have expertise in bacterial and viral diseases of both common and exotic/emerging pathogens. Emphasis is placed on molecular development of vaccines and testing in animal models for safety, immunogenicity, and efficacy.
U.S. Animal Vaccinology Research Coordination Network
The US Animal Vaccinology Research Coordination Network is an initiative of USDA NIFA to bring together the breadth of stakeholders with interest in advancing vaccine research and improving vaccine-based disease control in agricultural and aquacultural species.
More on the US Animal Vaccinology Research Coordination Network
Connecticut Veterinary Medical Diagnostic Laboratory
The Connecticut Veterinary Medical Diagnostic Laboratory provides top quality diagnostic services to our clients, who are comprised of veterinarians, members of the agricultural industry, owners of companion, zoo, and aquatic animals, stewards of Connecticut wildlife, and residents of Connecticut, New England, and beyond. We work cooperatively with federal and state veterinary agencies to enhance disease surveillance and response.
More about the Connecticut Veterinary Medical Diagnostic Laboratory
Institute for Systems Genomics
The Institute for Systems Genomics was established in 2012 to capitalize on the emerging synergy among faculty engaged in genome-based research and training efforts from departments, schools and colleges across UConn campuses and our CT-based partner, the Jackson Laboratories for Genomic Medicine.